Therapeutic potentials of superoxide dismutase

Keywords: Oxidative stress, superoxide dismutase, therapeutic effects

Abstract

Superoxide dismutases (SODs) constitute a very important antioxidant defense against oxidative stress in the body. The enzyme acts as a good therapeutic agent against reactive oxygen species-mediated diseases. The present review describes the therapeutic effects of SOD in various physiological and pathological conditions such as cancer, inflammatory diseases, cystic fibrosis, ischemia, aging, rheumatoid arthritis, neurodegenerative diseases, and diabetes. However, the enzyme has certain limitations in clinical applications. Therefore, SOD conjugates and mimetics have been developed to increase its therapeutic efficiency. Here, an overview is provided of some in vivo therapeutic effects observed with SOD.

Author Biography

H. Younus, Interdisciplinary Biotechnology UnitAligarh Muslim UniversityAligarh, UP, India202002

Associate Professor

Interdisciplinary Biotechnology Unit

Published
2018-04-19
How to Cite
Younus, H. (2018). Therapeutic potentials of superoxide dismutase. International Journal of Health Sciences, 12(3). Retrieved from https://ijhs.org.sa/index.php/journal/article/view/2026
Section
Reviews